Summary
Diabetic patients are 2.5 times more likely to develop heart failure than people without diabetes. In many patients, the diabetes causes a type of heart dysfunction called cardiomyopathy, which is characterised by functional and structural abnormalities in the heart. Currently, the underlying causes of diabetic cardiomyopathy remain unknown, and there are no effective treatments.
The CARDIATEAM project aims to determine how distinct diabetic cardiomyopathy is from other forms of heart failure, and the extent to which type 2 diabetes contributes to its development and progression. The team will recruit 1 600 people with a range of cardiometabolic disorders, including people with diabetes, and follow them for 3 years. By studying this group in detail over time, the team hopes to be able to deliver biological markers that would indicate which diabetes patients are at greatest risk of developing diabetic cardiomyopathy, as well as a more detailed understanding of the disease.
Ultimately, the project results will make it easier to provide people with diabetes with more personalised approaches to managing their condition and preventing diabetic cardiomyopathy.
Participants
Show participants on mapEFPIA companies
- Bayer Aktiengesellschaft, Leverkusen, Germany
- Eli Lilly And Company LTD, Basingstoke, United Kingdom
Universities, research organisations, public bodies, non-profit groups
- Assistance Publique Hopitaux De Paris, Paris, France
- Consorcio Centro De Investigacion Biomedica En Red M.P., Madrid, Spain
- Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt GMBH, Neuherberg, Germany
- Hospices Civils De Lyon, lyon, France
- Institut National De La Sante Et De La Recherche Medicale, Paris, France
- Katholieke Universiteit Leuven, Leuven, Belgium
- Luxembourg Institute Of Health, Luxembourg, Luxembourg
- SIB Institut Suisse De Bioinformatique, CH-660-0733998-3, Genève, Switzerland
- Stichting Netherlands Heart Institute, Utrecht, Netherlands
- The Queen'S University Of Belfast, Belfast, United Kingdom
- Universita Degli Studi Di Torino, Turin, Italy
- Universitaetsklinikum Aachen, Aachen, Germany
- Universite D'Aix Marseille, Marseille, France
- Universiteit Maastricht, Maastricht, Netherlands
- University Of Dundee, Dundee, United Kingdom
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
- Inserm Transfert SA, Paris, France
- Opale, Paris, France
Patient organisations
- Universitatsklinikum Heidelberg, Heidelberg, Germany
Third parties
- Academisch Ziekenhuis Groningen, Groningen, Netherlands
- Centre D'Etude Et De Recherche Multimodal Et Pluridisciplinaire En Imagerie Du Vivant Gie, Bron Cedex, France
- Clinical Trial Center Maastricht, Maastricht, Netherlands
- Fundacio De Recerca Clinic Barcelona-Institut D Investigacions Biomediques August Pi I Sunyer, Barcelona, Spain
- Fundacio Hospital Universitari Vall D'Hebron - Institut De Recerca, Barcelona, Spain
- Fundacion Para La Investigacion Biomedica Del Hospital Gregorio Maranon, Madrid, Spain
- Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Fundacion, Barcelona, Spain
- Stichting Amsterdam Umc, Amsterdam, Netherlands
| Participants | |
|---|---|
| Name | EU funding in € |
| Assistance Publique Hopitaux De Paris | 387 500 |
| Consorcio Centro De Investigacion Biomedica En Red M.P. | 334 584 |
| Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt GMBH | 269 526 |
| Hospices Civils De Lyon | 137 084 |
| Inserm Transfert SA | 310 250 |
| Institut National De La Sante Et De La Recherche Medicale | 1 053 229 |
| Katholieke Universiteit Leuven | 94 783 |
| Luxembourg Institute Of Health | 588 156 |
| Metabrain Research (left the project) | 28 150 |
| Opale | 392 481 |
| SIB Institut Suisse De Bioinformatique, CH-660-0733998-3 | 648 000 |
| Stichting Netherlands Heart Institute | 21 875 |
| The Queen'S University Of Belfast | 30 000 |
| Universita Degli Studi Di Torino | 407 616 |
| Universitaetsklinikum Aachen | 138 750 |
| Universitatsklinikum Heidelberg | 124 975 |
| Universite D'Aix Marseille | 213 375 |
| Universiteit Maastricht | 140 625 |
| University Of Dundee | 550 000 |
| Third parties | |
| Name | Funding in € |
| Academisch Ziekenhuis Groningen | 107 812 |
| Centre D'Etude Et De Recherche Multimodal Et Pluridisciplinaire En Imagerie Du Vivant Gie | 65 625 |
| Clinical Trial Center Maastricht | 219 062 |
| Fundacio De Recerca Clinic Barcelona-Institut D Investigacions Biomediques August Pi I Sunyer | 87 750 |
| Fundacio Hospital Universitari Vall D'Hebron - Institut De Recerca | 50 879 |
| Fundacion Para La Investigacion Biomedica Del Hospital Gregorio Maranon | 132 287 |
| Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Fundacion | 50 000 |
| Stichting Amsterdam Umc | 102 635 |
| Universitair Medisch Centrum Utrecht (left the project) | 12 990 |
| Total Cost | 6 699 999 |
Geneviève Derumeaux
Institut National De La Sante Et De La Recherche Medicale