CarePath

Collaborative action and research for engagement, persistence and adherence in treatment & health

Summary

Thanks to advances in research, many chronic diseases can now be managed with medication. However, studies show that around half of all people living with a chronic disease do not take their prescribed medication for more than a year. There are many reasons for this, including a lack of patient support, social barriers such as the stigma associated with certain illnesses, and financial barriers.

The aim of CarePath is to deliver a ‘plug and play’ toolbox with resources to boost both adherence (i.e. the extent to which patients take their medication as prescribed in terms of timing, dosage and frequency) and persistence (i.e. the length of time between the start of treatment and the last dose before stopping treatment).

CarePath will focus on three common chronic conditions (obesity, type 2 diabetes, and cardiovascular diseases) and on both primary care settings (e.g. general practitioners and community pharmacists) and secondary care (including hospitals, outpatient clinics and other specialised care facilities).

As a first step, the project team will gather details of existing interventions to boost adherence and persistence, along with information on what interventions work for which patients in different situations. The project will also gather input from key stakeholders, including patients and healthcare providers, on what they need from these kinds of tools.

All of this will feed into a CarePath toolbox comprising both technological and social innovation strategies to enhance adherence and persistency and to build capacity for healthcare stakeholders. The toolbox will include mobile applications to empower patients and improve their interactions with healthcare providers. It will also support the use of patient-reported outcome and experience measures (PROMs and PREMs). Short questionnaires will facilitate the early detection of signs of low adherence, allowing rapid intervention. The ‘plug and play’ nature of the toolbox means it can easily be adapted to different healthcare settings and countries.

The team will test the toolbox in pilot studies in six European countries: Germany, Israel, the Netherlands, Poland, Spain, and Sweden. These countries were selected as the are geographically diverse and their populations have different levels of disease, social determinants of health and other factors. In addition, a proof-of-concept study will be carried out in people with type 2 diabetes treated at out-patient clinics in Germany.

Ultimately, the project hopes that its toolbox will provide patients with personalised support that will help them improve medication adherence and persistence. This will in turn contribute to better health outcomes, an enhanced quality of life, and lower healthcare costs.

Participants

  Show participants on map
Universities, research organisations, public bodies, non-profit groups
  • Academisch Ziekenhuis Groningen, Groningen, Netherlands
  • Bar Ilan University, Ramat Gan, Israel
  • Charite - Universitaetsmedizin Berlin, Berlin, Germany
  • Fundacio Institut D'Investigacio Sanitaria Illes Balears, Palma, Spain
  • Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt GMBH, Neuherberg, Germany
  • Hl7 Europe, Bruxelles / Brussel, Belgium
  • Institut Catala De La Salut, Barcelona, Spain
  • Landschaftsverband Rheinland, Koln, Germany
  • Rijksuniversiteit Groningen, Groningen, Netherlands
  • Rise Research Institutes Of Sweden AB, Boras, Sweden
  • Stichting Amsterdam Umc, Amsterdam, Netherlands
  • Stichting Vu, Amsterdam, Netherlands
  • Universitaetsklinikum Wuerzburg - Klinikum Der Bayerischen Julius-Maximilians-Universitat, Wurzburg, Germany
  • Universytet Medyczny W Lodzi., Lodz, Poland
  • Vastra Gotalandsregionen, Vanersborg, Sweden
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
  • Imagine AI B.V., Utrecht, Netherlands
  • Mama Producties BV, Eindhoven, Netherlands
  • Thaumatec SP ZOO, Wroclaw, Poland
  • Wavy Assistant B.V., Groningen, Netherlands
Patient organisations
  • Asociación Bariátrica Híspalis Nacional, Santander, Spain
  • Israel Diabetes Association, Rishon LeZyion, Israel
  • Ogolnopolskie Stowarzyszenie Pacjentow ze Schorzeniami Serca i Naczyn Ecoserce, Milosc, Poland
  • Riksforbundet HjartLung, Stockholm, Sweden
  • The European Coalition For People Living With Obesity Company Limited By Guarantee, Dublin, Ireland
Third parties
  • Fundacio Institut Universitari Pera La Recerca A L'Atencio Primaria De Salut Jordi Gol I Gurina, Barcelona, Spain
  • Institut De Investigacio En Ciencies De La Salut Germans Trias I Pujol, Badalona Barcelona, Spain
IHI industry partners
  • A. Menarini - Industrie Farmaceutiche Riunite SRL, Firenze, Italy
  • Abbott GMBH, Wiesbaden, Germany
  • Biocorp Production, Issoire, France
  • Eli Lilly And Company, Indianapolis, United States
  • Institut De Recherches Internationales Servier, Gif-Sur-Yvette, France
  • Iqvia AG, Rotkreuz, Switzerland
  • Lilly Deutschland GmbH, Bad Homburg, Germany
  • Lilly France, Neuilly-sur-Seine Cedex, France
  • Menarini Benelux, Machelen, Belgium
  • Menarini Ricerche S.A, Pomezia, Italy
  • Novo Nordisk A/S, Bagsvaerd, Denmark
  • Pfizer Inc, New York City, United States
  • Pfizer Limited, Sandwich, United Kingdom
  • Pfizer R&D UK Limited, Sandwich, United Kingdom
  • Pfizer SLU, Madrid, Spain

Participants
NameEU funding in €
Academisch Ziekenhuis Groningen749 596
Asociación Bariátrica Híspalis Nacional25 000
Bar Ilan University568 151
Charite - Universitaetsmedizin Berlin486 660
Fundacio Institut D'Investigacio Sanitaria Illes Balears340 066
Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt GMBH980 000
Hl7 Europe409 250
Imagine AI B.V.45 000
Institut Catala De La Salut84 025
Israel Diabetes Association25 000
Landschaftsverband Rheinland164 625
Mama Producties BV299 063
Ogolnopolskie Stowarzyszenie Pacjentow ze Schorzeniami Serca i Naczyn Ecoserce25 000
Rijksuniversiteit Groningen531 859
Riksforbundet HjartLung25 000
Rise Research Institutes Of Sweden AB700 661
Stichting Amsterdam Umc1 299 531
Stichting Vu493 750
Thaumatec SP ZOO247 500
The European Coalition For People Living With Obesity Company Limited By Guarantee224 000
Universitaetsklinikum Wuerzburg - Klinikum Der Bayerischen Julius-Maximilians-Universitat220 095
Universytet Medyczny W Lodzi.383 725
Vastra Gotalandsregionen338 625
Wavy Assistant B.V.2 457 000
 
Third parties
NameFunding in €
Fundacio Institut Universitari Pera La Recerca A L'Atencio Primaria De Salut Jordi Gol I Gurina47 818
Institut De Investigacio En Ciencies De La Salut Germans Trias I Pujol129 000
 
Total Cost11 300 000