Summary
Immune-mediated diseases are extremely diverse – patients with the same diagnosis may see the disease progress in very different ways, and respond differently to treatments. This is because the course of the disease is influenced by multiple factors, including the patient’s genes, immune system, environment, and the microbes living in their gut. Furthermore, all of these factors interact with and impact on one another. As a result, it is very hard to predict how the disease will develop in a specific patient, and which treatments will be effective.
The goal of ImmUniverse is to add to our understanding of two immune-mediated diseases: ulcerative colitis (in which the immune system attacks the colon), and atopic dermatitis (which affects the skin). It will use liquid biopsies to detect the immune cells circulating in the blood, and analyse how these interact with the tissues affected at the microenvironment scale. The project will follow a number of patients over time to see how the disease evolves.
Ultimately, the project’s findings should contribute to a better, more precise diagnosis for patients; and better information on how severe the disease is likely to be for each individual patient and how it will progress over time. Finally, the project will make it easier for doctors and patients to monitor how well a treatment is working.
Participants
Show participants on mapEFPIA companies
- Eli Lilly And Company LTD, Basingstoke, United Kingdom
- Glaxosmithkline Research & Development Limited, Brentford, Middlesex, United Kingdom
- Novartis Pharma AG, Basel, Switzerland
- Pfizer Limited, Sandwich, Kent , United Kingdom
- Sanofi-Aventis Deutschland GMBH, Frankfurt / Main, Germany
Universities, research organisations, public bodies, non-profit groups
- Aarhus Universitet, Aarhus C, Denmark
- Aarhus Universitetshospital, Aarhus, Denmark
- Ait Austrian Institute Of Technology GMBH, Wien, Austria
- Centre Hospitalier Regional Universitaire Nancy, Nancy Cedex, France
- Christian-Albrechts-Universitaet Zu Kiel, Kiel, Germany
- Erasmus Universitair Medisch Centrum Rotterdam, Rotterdam, Netherlands
- Forum Des Patients Europeens, 1040, Belgium
- Humanitas University, Pieve Emanuele, Italy
- Istituto Superiore Di Sanita, Roma, Italy
- Joanneum Research Forschungsgesellschaft Mbh, Graz, Austria
- Katholieke Universiteit Leuven, Leuven, Belgium
- Ludwig-Maximilians-Universitaet Muenchen, Munich, Germany
- Scuola Superiore Di Studi Universitari E Di Perfezionamento S Anna, Pisa, Italy
- Stichting Amsterdam Umc, Amsterdam, Netherlands
- Stichting Radboud Universitair Medisch Centrum, Nijmegen, Netherlands
- Universita Vita-Salute San Raffaele, Milano, Italy
- Universitaet Ulm, Ulm, Germany
- Universite Du Luxembourg, Esch-sur-Alzette, Luxembourg
- University of Cambridge, Cambridge, United Kingdom
- Vib Vzw, Zwijnaarde - Gent, Belgium
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
- Eurice European Research And Project Office GMBH, Saarbrücken, Germany
- Information Technology For Translational Medicine (Ittm) SA, Esch-sur-Alzette, Luxembourg
Patient organisations
- European Federation Of Asthma &Allergy Associations Ideell Forening, Brussels, Belgium
- European Federation Of Crohn'S And Ulcerative Colitis Associations, Bruxelles, Belgium
Third parties
- Humanitas Mirasole S.A, Rozzano (Mi), Italy
Participants | |
---|---|
Name | EU funding in € |
Aarhus Universitet | 197 848 |
Aarhus Universitetshospital | 353 596 |
Ait Austrian Institute Of Technology GMBH | 2 131 236 |
Centre Hospitalier Regional Universitaire Nancy | 163 784 |
Christian-Albrechts-Universitaet Zu Kiel | 2 915 000 |
Erasmus Universitair Medisch Centrum Rotterdam | 105 000 |
Eurice European Research And Project Office GMBH | 704 063 |
European Federation Of Asthma &Allergy Associations Ideell Forening | 50 250 |
European Federation Of Crohn'S And Ulcerative Colitis Associations | 50 313 |
Forum Des Patients Europeens | 11 781 |
Humanitas University | 1 842 149 |
Information Technology For Translational Medicine (Ittm) SA | 400 501 |
Istituto Superiore Di Sanita | 502 989 |
Joanneum Research Forschungsgesellschaft Mbh | 832 409 |
Katholieke Universiteit Leuven | 516 693 |
Ludwig-Maximilians-Universitaet Muenchen | 392 975 |
Scuola Superiore Di Studi Universitari E Di Perfezionamento S Anna | 360 000 |
Stichting Amsterdam Umc | 633 048 |
Stichting Radboud Universitair Medisch Centrum | 1 096 421 |
Universita Vita-Salute San Raffaele | 96 313 |
Universitaet Ulm | 210 000 |
Universite Du Luxembourg | 780 939 |
University of Cambridge | 507 794 |
Vib Vzw | 644 900 |
Total Cost | 15 500 002 |