Summary
Many diseases are still diagnosed, monitored and studied in part on the basis of biological samples that have been mounted on a glass slide and studied under a microscope. Today, that analysis is still carried out by a human pathologist, but what if the slides could be scanned and analysed using artificial intelligence (AI)? And what if they could be placed in a repository and made available to the scientific community? These are the questions the BIGPICTURE project hopes to answer.
The project aims to create a repository of digital copies of around 3 million slides covering a range of disease areas. This repository will then be used to develop artificial intelligence tools that could aid in the analysis of slides.
To achieve its goal, the project will first create the infrastructure needed to store, share and process millions of (often heavy) image files. Secondly, they will address legal and ethical issues to ensure patient privacy and data confidentiality issues are fully respected.
In total, the project plans to populate the repository with 3 million digital slides from humans as well as laboratory animals. along with all the information associated with them. These will provide the project with the data needed to develop AI pathology tools. Finally, the project aims to develop functionalities to facilitate the use of the database as well as the processing of images for diagnostic and research purposes.
In the long term, the project will develop sustainability plans to maintain and continue to develop the platform beyond the end of the IMI project.
This project is supported by the Innovative Medicines Initiative, a partnership between the European Union and the European pharmaceutical industry.
Achievements & News
October 2022
Bigpicture has uploaded the first datasets to its platform, which aims to apply artificial intelligence to the field of pathology.
Participants
Show participants on mapEFPIA companies
- Bayer Aktiengesellschaft, Leverkusen, Germany
- Boehringer Ingelheim Internationalgmbh, Ingelheim, Germany
- F. Hoffmann-La Roche AG, Basel, Switzerland
- Institut De Recherches Internationales Servier, Suresnes, France
- Janssen Pharmaceutica Nv, Beerse, Belgium
- Novartis Pharma AG, Basel, Switzerland
- Novo Nordisk A/S, Bagsvaerd, Denmark
- Pfizer Limited, Sandwich, Kent , United Kingdom
- Sanofi-Aventis Recherche & Developpement, Chilly Mazarin, France
- UCB Biopharma, Brussels, Belgium
Universities, research organisations, public bodies, non-profit groups
- Biobanks And Biomolecular Resources Research Infrastructure Consortium (Bbmri-Eric), Graz, Austria
- Digital Pathology Association Inc, Carmel, United States
- European Society Of Pathology, Brussels, Belgium
- Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., München, Germany
- Haute Ecole Specialisee De Suisse Occidentale, Delemont, Switzerland
- Hus-Yhtyma, Helsinki, Finland
- Institut Pasteur, Paris, France
- Linkopings Universitet, Linkoping, Sweden
- Medizinische Universitaet Wien, Vienna, Austria
- Medizinische Universitat Graz, Graz, Austria
- Philipps Universitaet Marburg, Marburg, Germany
- Region Ostergotland, Linkoping, Sweden
- Semmelweis Egyetem, Budapest, Hungary
- Stichting Het Nederlands Kanker Instituut-Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Netherlands
- Stichting Radboud Universitair Medisch Centrum, Nijmegen, Netherlands
- Technische Universitaet Muenchen, Muenchen, Germany
- Technische Universiteit Eindhoven, Eindhoven, Netherlands
- The European Institute For Innovation Through Health Data, Gent, Belgium
- The Leeds Teaching Hospitals National Health Service Trust, Leeds, United Kingdom
- Universitair Medisch Centrum Utrecht, Utrecht, Netherlands
- Universite De Liege, Liège, Belgium
- University Of Warwick, Coventry, United Kingdom
- Uppsala Universitet, Uppsala, Sweden
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
- Csc-Tieteen Tietotekniikan Keskus Oy, Espoo, Finland
- Deciphex Limited, Mornington Meath, Ireland
- Din Deutsches Institut Fuer Normung Ev, Berlin, Germany
- Gbg Forschungs GMBH, Neu-Isenburg, Germany
- Owkin France, Paris, France
- Phit BV, Utrecht, Netherlands
- Sectra AB, Linköping, Sweden
- Stichting Lygature, Utrecht, Netherlands
- Timelex, Brussel, Belgium
- Ttopstart BV, Bilthoven, Netherlands
Third parties
- Diagnexia Uk Limited, London, United Kingdom
- Katholieke Universiteit Leuven, Leuven, Belgium
- Umea Universitet, Umea, Sweden
- Universita' Degli Studi Di Milano-Bicocca, Milano, Italy
- University of Turku, Turku, Finland
Participants | |
---|---|
Name | EU funding in € |
Azienda Ospedaliera Per L Emergenza Cannizzaro (left the project) | 2 153 |
Biobanks And Biomolecular Resources Research Infrastructure Consortium (Bbmri-Eric) | 209 000 |
Csc-Tieteen Tietotekniikan Keskus Oy | 4 003 125 |
Cytomine Corporation SA (left the project) | 334 421 |
Deciphex Limited | 2 318 750 |
Digital Pathology Association Inc | 12 000 |
Din Deutsches Institut Fuer Normung Ev | 98 413 |
European Society Of Pathology | 60 000 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | 240 006 |
Gbg Forschungs GMBH | 72 000 |
Haute Ecole Specialisee De Suisse Occidentale | 300 000 |
Hus-Yhtyma | 900 000 |
Institut Pasteur | 378 125 |
Linkopings Universitet | 2 163 750 |
Medizinische Universitaet Wien | 619 430 |
Medizinische Universitat Graz | 232 000 |
Owkin France | 400 000 |
Philipps Universitaet Marburg | 600 000 |
Phit BV | 270 000 |
Region Ostergotland | 600 000 |
Sectra AB | 196 875 |
Semmelweis Egyetem | 72 000 |
Stichting Het Nederlands Kanker Instituut-Antoni Van Leeuwenhoek Ziekenhuis | 200 000 |
Stichting Lygature | 1 724 000 |
Stichting Radboud Universitair Medisch Centrum | 8 799 021 |
Technische Universitaet Muenchen | 312 000 |
Technische Universiteit Eindhoven | 240 000 |
The European Institute For Innovation Through Health Data | 60 000 |
The Leeds Teaching Hospitals National Health Service Trust | 950 150 |
Timelex | 240 000 |
Ttopstart BV | 160 000 |
Universitair Medisch Centrum Utrecht | 600 000 |
Universite De Liege | 1 625 375 |
University Of Warwick | 399 983 |
Uppsala Universitet | 2 325 000 |
Third parties | |
Name | Funding in € |
Diagnexia Uk Limited | 131 250 |
Katholieke Universiteit Leuven | 57 000 |
Umea Universitet | 300 000 |
Universita' Degli Studi Di Milano-Bicocca | 57 000 |
University of Turku | 57 000 |
Total Cost | 32 319 827 |