Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
Project factsheets
Learn more about the projects supported by IHI as well as the Innovative Medicines Initiative (IMI).
Displaying 143 projects and 3 programmes
Identifying digital endpoints to assess fatigue, sleep and activities in daily living in neurodegenerative disorders and immune-mediated inflammatory diseases
Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood
Development of rapid point-of-care test platforms for infectious diseases
Remote Assessment of Disease and Relapse in Central Nervous System Disorders
Center of excellence – remote decentralised clinical trials
Remote assessment of disease and relapse – Alzheimer’s disease
Psychiatric Ratings using Intermediate Stratified Markers: providing quantitative biological measures to facilitate the discovery and development of new treatments for social and cognitive deficits in AD, SZ, and MD
PharmaLedger
Gravitate–Health: Empowering and equipping Europeans with health information for active personal health management and adherence to treatment
Integration of heterogeneous data and evidence towards regulatory and HTA acceptance
Chemical manufacturing methods for the 21st century pharmaceutical industries
European Patients' Academy on Therapeutic Innovation
COVID-19 infections - remote early detection
Recognising Adverse Drug Reactions
Ebola and other filoviral haemorrhagic fevers
Communication strategy and tools for optimizing the impact of Ebola vaccination deployment
Central repository for digital pathology
Zoonotic anticipation and preparedness initiative
Organising mechanistic knowledge about neurodegenerative diseases for the improvement of drug development and therapy
Synthetic healthcare data governance hub
Imaging for patient benefit in arthritis
New models for preclinical evaluation of drug efficacy in common solid tumours
European Bank for induced pluripotent Stem Cells
Delivering European Translational Information & Knowledge Management Services
Framework to IMPROVE the integration of patient generated health data to facilitate value based healthcare
Kinetics for Drug Discovery
A minituarized disposable molecular diagnostics platform for combatting coronavirus infections
Shortening the path to rare disease diagnosis by using newborn genetic screening and digital technologies
Methods for systematic next generation oncology biomarker development
Ultra-fast molecular filovirus diagnostics
Improving beta-cell function and identification of diagnostic biomarkers For treatment monitoring in diabetes
Propelling the shift toward the future of circular, safe and sustainable packaging and single use device ecoDesigned solutions through healthcare environments
Prediction of Alzheimer’s disease using an AI driven screening platform
European programme in Pharmacovigilance and Pharmacoepidemiology
The Open Pharmacological Concepts Triple Store
Incorporating real-life clinical data into drug development
Advancing safe and sustainable by design practices in pharmaceutical manufacturing
Development of a prophylactic Ebola vaccine using an heterologous prime-boost regimen
Research in Europe and diversity inclusion
Better control and treatment of immune-mediated diseases by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies
Behavioral and adherence model for improving quality, health outcomes and cost-effectiveness of healthcare
Electronic Health Records Systems for Clinical Research
Biomarkers for Enhanced Vaccine Immunosafety
Real-world implementation, deployment and validation of early detection tools and lifestyle enhancement
Stem cells for biological assays of novel drugs and predictive toxicology
Biomarkers and molecular tumour classification for non-genotoxic carcinogenesis
Building a reproducible single-cell experimental workflow to capture tumour drug persistence
Synthetic data generation framework for integrated validation of use cases and AI healthcare applications
Mobile Filovirus Nucleic Acid Test
Integrating bioinformatics and chemoinformatics approaches for the development of Expert systems allowing the in silico prediction of toxicities
Innovations to accelerate vaccine development and manufacture
Real world outcomes across the AD spectrum for better care: multi-modal data access platform
Rapid and secure AI imaging based diagnosis, stratification, follow-up, and preparedness for coronavirus pandemics
European Medical Information Framework
WEB-RADR 2
Improving the care of patients suffering from acute or chronic pain
European Medicines Research Training Network
Amyloid imaging to prevent Alzheimer’s disease
Surrogate markers for micro- and macro-vascular hard endpoints for innovative diabetes tools
Patients active in research and dialogues for an improved generation of medicines: advancing meaningful patient engagement in the life cycle of medicines for better health outcomes
Imaging and advanced guidance for workflow optimization in interventional oncology
Optimal treatment for patients with solid tumours in Europe through artificial intelligence
FAIRplus
Understanding chronic pain and improving its treatment
Biomarkers in atopic dermatitis and psoriasis
Accelerated development of appropriate patient therapies: a sustainable, multi-stakeholder approach from research to treatment-outcomes
Ebola virus: modern approaches for developing bedside rapid diagnostics
The GetReal Initiative
Building an ecosystem for better monitoring and communicating of medication safety in pregnancy and breastfeeding: validated and regulatory endorsed workflows for fast, optimised evidence generation
Investigating mechanisms and models predictive of accessibility of therapeutics (IM2PACT) into the brain
Be The Cure
Ensuring the future of EUPATI beyond 2020
Preparing for RSV immunisation and surveillance in Europe
Unleashing a comprehensive, holistic and patient centric stroke management for a better, rapid, advanced and personalised stroke diagnosis, treatment and outcome prediction
Translational Safety Biomarker Pipeline (TransBioLine): Enabling development and implementation of novel safety biomarkers in clinical trials and diagnosis of disease
PERtussIS COrrelates of Protection Europe
Modern approaches for developing antivirals against SARS-CoV 2
Drug Disease Model Resources
European Quality In Preclinical Data
Prediction of cognitive properties of new drug candidates for neurodegenerative diseases in early clinical development
Autism Innovative Medicine Studies – 2 – Trials
Accelerating development and improving access to CAR and TCR-engineered T cell therapy
Big data for better outcomes, policy innovation and healthcare system transformation
Respiratory syncytial virus consortium in Europe
Pharmacoepidemiological research on outcomes of therapeutics by a European consortium
Vaccine safety and immunogenicity signatures of human responses to VSV-ZEBOV
Combining diagnostic data and interventional approaches for futureproof cardiology care
Prostate cancer diagnosis and treatment enhancement through the power of big data in Europe
Immune safety avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies
Elevating the future of cancer care with alpha theranostics
Theranostics ecosystem for personalised care
Individualised care from early risk of cardiovascular disease to established heart failure
Novel methods leading to new medications in depression and schizophrenia
Unbiased biomarkers for the prediction of respiratory disease outcomes
European Autism Interventions - a Multicentre Study for Developing New Medications
European Gram-negative Antibacterial Engine
Model-based preclinical development of anti-tuberculosis drug combinations
Identification of the molecular mechanisms of non-response to treatments, relapses and remission in autoimmune, inflammatory, and allergic conditions
Quantative imaging in cancer:connecting cellular process with therapy
Guiding multi-modal therapies against MRD by liquid biopsies
Patient lifestyle and disease data interactium
Precision medicine platform in neurodegenerative disease
Comprehensive methodological and operational approach to clinical trials in rare and ultra-rare diseases
Improving patient outcomes and reducing cognitive load of clinical staff in intensive care through medical-device interoperability and an open and secure IT ecosystem
Enhacing TRANslational SAFEty Assessment through Integrative Knowledge Management
Framework for clinical trial participants data reutilization for a fully transparent and ethical ecosystem
H2O Health outcomes observatory
Integrated immunoprofiling of large adaptive cancer patients cohorts
Specific imaging of immune cell dynamics using novel tracer strategies
Translational approaches to disease modifying therapy of type 1 diabetes: an innovative approach towards understanding and arresting type 1 diabetes.
Evaluation of a production ready portable, point-of-need platform (instrument and reagents), direct from nasal swab test for the molecular diagnostic detection of COVID-19 infection
Proton versus photon therapy for esophageal cancer - a trimodality strategy
Robust automation and point of care identification of COVID
Real world handling of protein drugs - exploration, evaluation and education
The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use
European prevention of Alzheimer’s dementia consortium
Establishing international standards in the analysis of patient reported outcomes and health-related quality of life data in cancer clinical trials
Harmonised approach to early feasibility studies for medical devices in the European Union
Assessing risk and progression of prediabetes and type 2 diabetes to enable disease modification
GRIP on MASH: global research initiative for patient screening on MASH
Patient Preferences in benefit risk assessments during the drug life cycle
Machine learning ledger orchestration for drug discovery
Efficiently networking European neurodegeneration research
Applied public-private research enabling osteoarthritis clinical headway
Increasing lutetium production, while leveraging metabolic imaging to enhance theranostics effectiveness
European Modular Education and Training Programme in Safety Sciences for Medicines
EU patient-centric clinical trial platform
conect4children - Collaborative network for European clinical trials for children
European Lead Factory
Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury
Diabetes research on patient stratification
Sarcopenia and physical frailty in older people: multi‐component treatment strategies
Molecular basis of the bacterial cell wall permeability
Integrated control and sensing platform for biopharmaceutical cultivation process high-throughput development and production
New Drugs for Bad Bugs
Modelling neuron-glia networks into a drug discovery platform for pain efficacious treatments
Oral biopharmaceutics tools
Alzheimer's disease apolipoprotein pathology for treatment elucidation and development
Anti-Biopharmaceutical Immunization: Prediction and Analysis of Clinical Relevance to Minimize the Risk
Patient-centric blood sampling for improved healthcare (Project-COMFORT)
Accelerated development of vaccine benefit-risk collaboration in Europe
Models of patient engagement for Alzheimer’s disease
Safer and Faster Evidence-based Translation
Antimicrobial Resistance Accelerator
Combatting Bacterial Resistance in Europe